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Covid-19: First case of Multisystem Inflammatory Syndrome in Children (MIS-C) reported in Manipur

Many children may have been infected without symptom but may develop this disease later.

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Imphal: Manipur reported its first case of Multisystem Inflammatory Syndrome in Children (MIS-C), a post-Covid-19 complication, which is rare but a life threatening disease here on Saturday.

A 10-year-old boy who was admitted at the Mother’s Care Children Hospital and Research Centre, Sagoldband Moirang Leirak, Imphal a few days ago, had a fever for five days, severe headache, profound weakness, severe pain abdomen at the time of admission. However, his Covid-19 RTPCR Test was negative. 

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Later, he developed rashes, redness of eyes, red lips and tongue along with lymphnode enlargement in the neck.  His (LVEF) left heart function was depressed and went to shock. He was managed in the Pediatric Intensive Care Unit of the hospital, needing multiple support. Suspecting MIS-C, his antibody test was sent for Covid-19 and was reported to be positive, a statement by the hospital authorities said.

With due diligence care the boy was  discharged well on Friday, it added. 

It further pointed out that most of the children infected with Covid-19 have mild symptoms or are vastly asymptomatic. But a serious condition that occurs in children infected with Covid-19 after being asymptomatic or mildly symptomatic is broadly called Multisystem Inflammatory Syndrome (MIS-C). 

In this clinical entity, children developing such diseases have multiple organs or tissue involvement.  They can have heart involvement that can lead to failure. Lung, kidneys, gut, blood vessels, skin, eyes and brain can get involved too. Common signs are fever, headache more than 24 hours, vomiting, diarrhea, pain abdomen, skin rashes, profound tiredness, rapid breathing, red eyes,  lymphnode  enlargement and redness of tongue and lips.. These signs can easily be fitting to many childhood diseases such as Kawasaki Disease or Acute pyomenigitis, it further highlighted.  

It further advised that parents as well as caregivers need to have a high suspicion of this entity at the backdrop of the pandemic. Many children may have been infected without symptom but may develop this disease later. The early and optimum intervention will be of utmost importance for favourable outcomes in our children, it cautioned. 

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